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Ann Rheum Dis (2020) 79(6):68599

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Similarly, large well-conducted studies with pentoxifylline, a non-specific TNF inhibitor, failed to show any mortality benefit over prednisolone alone [26,44]

In the absence of a unified conceptual framework, distinctions between neuroprotection, symptomatic treatment, and disease modification often become obscured, risking the conflation of mechanistic plausibility with demonstrable clinical benefit

JAMA 309:570577 Atladttir H, Thorsen P, stergaard L, Schendel DE, Lemcke S, Abdallah M, Parner ET (2010) Maternal infection requiring hospitalization during pregnancy and autism spectrum disorders