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Yet cash-pay barriers keep real-world penetration below 200,000 patients so far, implying enormous headroom once biosimilar pricing compresses

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Apart from its main substrate H 2 O 2 , the CAT enzyme could also process other oxidative species such as O 2 - , OH, 1 O 2 , hypochlorous acid (HOCl), NO, and peroxynitrite (ONOO - )

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