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The STEP-1 trial showed 14.9% mean weight reduction at 68 weeks with Semaglutide 2.4mg weekly versus 2.4% on placebo in adults with BMI 30 or above

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Location: Primarily found in pancreatic beta cells, but also in adipose tissue, bone, and the central nervous system

Quick summary Semaglutide and Tirzepatide are prescription injectable medications used to help with weight loss when paired with lifestyle change and medical supervision

Several patient-specific factors should guide the decision about when to administer GLP-1 medications

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