Targeting programmed cell death in metabolic dysfunction-associated fatty liver disease (Mafld): a promising new therapy
Importantly, if you have previously been treated with the 2.4mg weekly injection, you may be able to transition directly to the 25mg daily tablet without starting from the bottom of the dose schedule
Wegovy has been approved to reduce the risk of major heart problems, and in August Lilly released data showing the heart-protective qualities of the diabetes treatment Mounjaro, which has the same main ingredient as Zepbound
Treatment focuses on dietary changes to avoid lactose, use of lactase enzyme supplements, and incorporating lactose-free alternatives to manage symptoms and ensure nutritional needs are met, with severe cases requiring medical consultation
More serious but rare complications include pancreatitis, gallbladder disease (particularly with rapid weight loss), and potential thyroid C-cell tumours (observed in animal studies)
PMID: 34942372