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Plasma concentrations of GHK-Cu are relatively high in young adults (approximately 200 ng/mL) and decline significantly with age, dropping to around 80 ng/mL by age 60

To identify nodose (ND) neurons in co-culture experiments, nodose ganglia were collected from a transgenic mouse line, generated by crossing NeuroD1-cre mice (provided by Andrew Leiter) with a ROSA26EYFP reporter line

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The peptide binds directly to these cells and triggers regenerative responses

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[Abstract]2022 Nov 15;23(1):55