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Since then, several GLP-1s for obesity have been approved for new indications, such as secondary cardiovascular risk reduction (Wegovy), sleep apnea (Zepbound) and metabolic dysfunction-associated steatohepatitis, or MASH (Wegovy)

Its pivotal Phase 3 programmes (ATTAIN for obesity and ACHIEVE for type 2 diabetes) demonstrated significant weight loss, meaningful A1C reductions and improvements in cardiometabolic risk factors, with a safety profile broadly consistent with the injectable GLP-1 class, including a boxed warning for thyroid C-cell tumour risk

A., Koerts, J., Nieuwland, R., Kalsbeek-Batenburg, E

A continuacin, se analizan los principales efectos no deseados que se pueden asociar con su uso