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The effects of GLP-1 infusion in the hepatic portal region on food intake

For many patients, they offer meaningful benefits when used under proper medical supervision

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It is unclear where DSIP is synthesized

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As well as these broader systemic effects, it has also been suggested that DPP-4 may be able to modulate -cell function as part of a paracrine system involving GLP-1 produced locally within the pancreatic islets