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Retrieved from Hollstein, T., Heinitz, S., Ando, T., et al

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doi: 10.1111/tpj.13666 64 ZengJ

Indirectly, weight loss may lessen mechanical friction in flexural sites, reduce moisture and maceration, and dampen the obesity-related state of low-grade systemic inflammation

See below for discussion of the uric acid-lowering agents, allopurinol and probenecid

Once the fat is dissolved, the body naturally eliminates the fat through the lymphatic system, resulting in a reduction of fat in the treated area over time