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Researchers interested in whether those pathways interact use a fixed-ratio preparation so that the exposure is identical across samples rather than assembled by hand each time

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These apoptotic processes involve the activation of cysteine-aspartic proteases, such as caspases and calpain, which are activated by the interactions of various neurochemical, cellular, and molecular pathways, including ERK, p38 MAPK, and JAK/STAT (Thapa et al., 2021)