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These results mean that the new agents targeting the endocannabinoid system are potential and promising therapeutics for further research

Dixon first discovered and named ferroptosis, the critical role of GPX4 in the inhibition of ferroptosis in his study has received widespread attention, mainly in the antioxidant axis system x c - -GSH-GPX4 ( c - is inhibited, obstruction of the cystine transport pathway can decrease GSH and GPX4, which can lead to cell death due to ongoing oxidative stress ( Figure 1A )

Other effects of activation of GLP-1 receptors include inhibition of glucagon secretion combined with inhibition of gastric emptying, suppression of appetite and cardioprotective effects [5]

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