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doi: 10.1097/00003246-200104000-00005 49 SefikEQuRJunqueiraCKaffeEMirzaHZhaoJet al

Injection sites commonly include the abdomen, thigh, or upper arm

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For example, ER stress activates DNA damage inducible transcript 3 (DDIT3, also known as CHOP)- and mitogen-activated protein kinase 8 (MAPK8, also known as JNK)-dependent apoptosis pathways, whereas heat shock protein family A member 5 (HSPA5, also known as BIP) SSG at Cys420/441 modulates ATPase activity and protein folding, paradoxically suppressing apoptosis 49

In vitro kinase assays using recombinant MPK6 and protein fragments identified a critical phosphorylation site (37)

Ghezzi et al., 2019