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In addition, the authors found that after acetaminophen became commonly used to treat circumcision pain after 1995, there was a strong correlation between country-level ( n = 9) autism/ASD prevalence in males and a countrys circumcision rate ( r = 0.98)

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This was not possible for the in vitro and in vivo studies, as these experiments were performed by individual investigators who were aware of the experimental groups and treatment outcome

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