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These small molecules bind to mRNA and prevent it from being translated into a protein in the cell ribosome, thus abrogating the downstream effects of that proteins signaling (Chan 2006

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doi: 10.1345/aph.1Q629 146 SivakumarTMechanicOFehmieDAPaulB

EHMT2/G9a stood out as a potential target: it is an epigenetic regulator expressed in immune cells, including macrophages, and its previously determined half maximal effective concentration (EC 50 ) (PubChem AID: 504332) matches the effect range (10100 M) seen in our study 39

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Until then, the use of AOD 9604 remains a topic of both potential promise and cautious consideration