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Testing focuses primarily on device performance characteristics (spray pattern, plume geometry, droplet size distribution by laser diffraction), formulation stability, and chemical assay

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In mouse models of highfat dietinduced obesity, it treatment significantly reduced mRNA and protein expression of TNF, IL6, and other inflammatory factors in adipose tissue and decreased macrophage infiltration - a hallmark of adipose inflammation

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doi: 10.1074/jbc.R900010200 43 OhgamiK.ShiratoriK.KotakeS.NishidaT.MizukiN.YazawaK.et al