semaglutide prediabetes weight loss trial progression to diabetes Efficacy and safety of once-weekly 2·4 mg versus placebo in people with obesity and (STEP 10): a randomised, double-blind, placebo-controlled, multicentre phase 3 semaglutide prediabetes weight loss trial

These effects are usually mild to moderate and tend to improve over time

Maintaining protein intake is vital for preserving lean muscle, supporting stable energy, and preventing fatigue or nutrient loss

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Study Used AI to Analyze Real-World Patient Reports To better understand how people experience GLP-1 drugs outside of clinical trials, researchers used AI to analyze Reddit posts from 2019 to 2025

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People with certain medical conditions, like type 2 diabetes, may see additional benefits beyond weight loss