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At the start of your program, youll notice a reduced appetite and curbed cravings

Muscle and bone health: lean mass and sarcopenia risk Substantial weight loss achieved with GLP-1-based therapies has raised concerns regarding potential adverse effects on muscle mass and function

Self-care measures for managing injection site lumps: Avoid manipulation : Resist the urge to massage, squeeze, or repeatedly touch the lump

In practical terms, that means semaglutide may be showing a stronger signal for mental-health and addiction-related benefits than some alternatives that act on similar pathways

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Similarly, the LEADER trial with liraglutide showed a numerically higher, though non-significant, rate of diabetic retinopathy events compared to placebo (HR, 1.15