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14.1 Monotherapy A total of 1262 patients with type 2 diabetes participated in two double-blind, placebo-controlled studies, one of 18-week and another of 24-week duration, to evaluate the efficacy and safety of JANUVIA monotherapy

10.1016/j.cell.2013.12.010 151 YangW

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It is a membrane stabilizer and counteracts gut-leaky syndromehas profound cytoprotective activityand specifically [controls] the VEGF [vascular endothelial growth factor] and NO [nitric oxide] pathways, in particular the prostaglandin pathway (Sikiric et al, 2022)

[1] Because no GLP-1 patches are currently FDA-approved or commercially available , there is no established clinical protocol for their application

Historically, copper compounds have been used as paint pigments, wood preservatives and pesticides 4