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In particular, ER UPR-mediated activation of JNK has been linked to the development of insulin resistance and diabetes by inhibition of insulin receptor signaling (131)

Other studies have indicated that enteroendocrine cells may migrate at a rate 5 times slower than other epithelial cells 105

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Exploring the Quantitative Relationship Between the Level of MDR1 Transcript, Protein and Function Using Digoxin as a Marker of MDR1-Dependent Drug Efflux Activity