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Consistently, this response was accompanied by a notable increase in SL levels in leaves, along with enhanced expression of SL biosynthetic genes, including VvCCD7 and VvCCD8 72

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Beyond lipid metabolism, transcriptomic analysis also revealed that SR4 induces a broader metabolic reprogramming in the liver of db/db mice

In addition to their cargo, the EVs themselves may carry signatures of ferroptosis

Short-term benefit of flumazenil with the absence of prolonged effects is not unsurprising given its short elimination half-life (0.71.3 h), and thus it is not currently advocated for routine clinical use to treat HE