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Sources The Effectiveness of Cobalamin (B12) Treatment for Autism Spectrum Disorder: A Systematic Review and Meta-Analysis Journal of Personalized Medicine (2021) Vit B12 supplement of 500 g/d for eight weeks does not normalize urinary methyl-malonic acid or other biomarkers of vitamin B12 status in elderly people J Nutr

AHK-Cu (alanyl-histidyl-lysine-copper) has a slightly different amino acid chain but similar biological activity

However, only Methylcobalamin is biologically active without conversion

Here is a breakdown of active B12 levels by age and gender: Source: 1,458 EDGE customer blood test results Apr 2023 March 2025