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Extra caution is warranted for people with: Gastroparesis or delayed gastric emptying GLP-1 medications significantly delay gastric emptying and are generally not recommended in severe gastroparesis

During a VSG procedure, a large portion of the stomach is removed, reducing the amount of food a patient can consume and altering hunger hormones like ghrelin, which regulates appetite

This interference is primarily due to orlistat's ability to reduce fat absorption, which in turn impacts the bioavailability of these medications

All data were presented as Mean SEM unless otherwise stated

There is insufficient data for nursing mothers

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