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Seek immediate medical attention for severe abdominal pain (possible pancreatitis or gallbladder disease), persistent vomiting leading to dehydration (risk of acute kidney injury), visual changes (potential diabetic retinopathy complications), or signs of serious allergic reaction

This is because alpha lipoic acid can make blood sugar drop too low

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The anti-inflammatory mechanisms, including NF-kB suppression, TNF-alpha reduction, and macrophage polarization, are directly relevant to IBD pathology