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Proliferation assay 1919 isogenic cells, MDA-MB-468 BRCA PHGDH wild type cells and MDA-MB-231 BRCA cells characterized by PHGDH amplification were seeded (7500 cells/well) in 96-well plates (Sigma-Aldrich) and incubated at 37 C for 24 h to obtain optimal adherence to the surface
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Association between glutathione S-transferase P1, T1, and M1 genetic polymorphism and survival of patients with metastatic colorectal cancer
PKA also affects integrin-dependent migration in a variety of cells (119) and PKA and its phosphorylated substrates are enriched in cellular protrusions (111, 120)
Owing to its rapid, competitive, and invasive growth, it is often regarded as a weed in many regions