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Notably, Hcy levels are lower during pregnancy than in non-pregnant women due to an increase in the glomerular filtration rate, plasma volume, and enhanced fetal absorption [146]

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Although the mechanism of acetaminophen toxicity is well recognized, the clinical implications of age-related differences and the ontogeny of hepatic pathways may not be commonly appreciated

This phenomenon could be attributed to the fact that ethanol exposure accelerated the pathological process of AD, which in turn damaged the antioxidant capacity in APP/PS1 mice