Specific proteins reported to be upregulated in CVD (but downregulated with semaglutide treatment, after adjusting for effects of weight loss and HbA 1c reduction) include NPPB (NT-proBNP, released from cardiomyocytes on ventricular distension) 37 , ANGPT2 (involved in vascular remodeling and angiogenesis) 38 , CD93 (involved in cardiovascular homeostasis) 39 , MSR1 (involved in lipid metabolism and immune function) 40,41 , and THBS2 and TNC (both involved in extracellular matrix remodeling) 42
doi: 10.1016/j.ajpc.2024.100679 PMID: 38779187 Vosoughi K et al (2022): Effects of GLP-1 agonists on proportion of weight loss in obesity with or without diabetes: Systematic review and meta-analysis
Delivery Method: Subcutaneous Injection
Instead of full meals, aim for small protein anchors throughout the day
Comprehensive Metabolic Reconditioning
Christopher McGowan, an obesity medicine physician and founder of True You Weight Loss in Cary, North Carolina, previously told TODAY.com