[1] Majeed M, Nagabhushanam K, Arumugam S, et al
Its especially problematic for people in between the clinical diagnoses of overweight and obesity. Heres why using GLP-1s to lose 10 to 30 pounds has benefits beyond a smaller waistline
Microbial ecology: Human gut microbes associated with obesity
These adverse events have been addressed through extensive phase 3 registration trials, including cardiovascular outcome trials for both its subcutaneous (SUSTAIN) and oral (PIONEER) formulations [9], including gastrointestinal symptoms, acute kidney injury, gallbladder issues, thyroid cancer, and pancreatic complications like pancreatitis and pancreatic cancer [10]
In this regard, metformin may play an important role, due to its potential impact on the innate immune response and the generation of ROS caused by inflammatory cytokines
Symptoms can vary between individuals