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These pulsatile as well as nychthemeral secretory patterns are pre-eminent physiological features of healthy GH release and are critical to physiological regulation and long-term activation of the GH neuroendocrine axis

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These studies should be interpreted with great caution and reservation as to their applicability to the normal intestine in individuals or damaged intestine in patients with trauma, severe burns or patients with obstructed bowel or circulatory collapse [79]