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*Correspondence: Xue Li, [email protected] This article was submitted to Inflammation, a section of the journal Frontiers in Immunology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Under the stimulation of cigarette smoke or other harmful substances, the respiratory tract epithelium secretes inflammatory cytokines and chemokines, such as leukotriene B4 (LTB4), interleukin-6 (IL-6), IL-8 (CXCL8) and tumour necrosis factor- (TNF-), and other mediators in the lungs