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Although the study primarily reports clinical outcomes, changes in specific biomarkers indirectly suggest potential mechanisms of action of GLP-1RAs

However, symptoms may temporarily worsen following dose increases

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It does this by interacting with NMDA receptors (cells in your brain) and the hypothalamic-pituitary-adrenal (HPA) axis (essentially your bodys stress response system)

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Also, in experimental studies, Ipamorelin has been evaluated for its impact on bone markers, muscle repair mechanisms and gastric motility parameters[1, 2, 3]