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106 TNF- and IL-1 also regulate chemokine (C-C motif) ligand 3 (CCL3) expression in NP cells and promote macrophage infiltration through the CCL3-CCR1 axis in degenerated herniated discs

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Constipation, diarrhea, and occasional vomiting round out the GI picture

Khan RA, Khan MR, Sahreen S