Curcumin is a natural phenolic antioxidant, can increases Nrf2 transfer into the nucleus and promote HO-1 expression, reducing the excessive downregulation of GPx4 [111]
Close behind, Trulicity (dulaglutide) from Eli Lilly maintains a strong foothold with over $7 billion in annual sales
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Furthermore, there are indications that GLP-1s may help reduce compulsive eating behaviors and the persistent thoughts about food that many individuals with obesity experience
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10.1038/s41419-020-2298-2 90 LiJ.DingY.ZhangJ.ZhangY.CuiY.ZhangY.et al (2024c)