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Comments received after that date but by July 22, 2026, will be taken into consideration by FDA

In addition to movement disorder, different non-motor symptoms such as dementia, psychosis and depression are observed in patients, which increase in late stages of disease

A1: 5-Amino-1MQ peptide is used in laboratory studies to investigate NNMT inhibition, NAD-related metabolic pathways, adipocyte biology, and cellular energetics in in vitro, ex vivo, and non-clinical in vivo models