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Molecular Life Sciences CMLS 65, 13901402

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The ratio of eumelanin to pheomelanin is genetically determined by a number of factors including the degree of base-line functional activity of the enzymes and proteins driving the mixed melanogenesis, by the melanocortin 1 receptor (MC1R) genetic polymorphism, and by the amount of the tyrosine in the melanosome [6]

D12492, Research Diets, Inc.) at 7 weeks of age and maintained for 15 weeks before allocation into weight-matched groups (n = 8)