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They are deposited in lysosomes in the form of lipofuscin (lipofuscinogenesis), which, in turn, is deposited underneath the RPE as a drusen (drusogenesis) [10]

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For example, increased uptake and trafficking of linoleic acid induce lipid peroxidation and apoptosis in CD44 - CD4 + T cells [105]

The funding source had no role in study design, data collection, analysis and interpretation, writing of the report, and decision to submit the article for publication

showed that for CD4 + Th17 cells, OL cytotoxicity was perforin/granzyme-dependent 40