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In the citric acid cycle, Vitamin B3 (Niacin) is involved in the formation of acetyl-CoA while conversion of its co-enzyme takes places from NAD+ (nicotinamide adenine dinucleotide) to NADH (12)

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Research on both mice and humans has highlighted the essential role of IL-33 in stimulating ILC2s and Th2 cells to secrete type 2 cytokines, such as IL-5 and IL-13, which trigger allergic responses driven by the innate immune system [178,179,180]