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Br J Clin Pharmacol 62(3):309315 [DOI] [PMC free article] [PubMed] [Google Scholar] Vree TB, Dammers E, Ulc I, Horkovics-Kovats S, Ryska M, Merkx I (2003) Differences between lovastatin and simvastatin hydrolysis in healthy male and female volunteers: gut hydrolysis of lovastatin is twice that of simvastatin

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A larger follow-up RCT (n=72 older adults) confirmed these findings, additionally demonstrating improvements in gait speed (+0.14 m/s), grip strength, 6-minute walk distance, waist circumference reduction, and systolic blood pressure reduction (Kumar et al., J Gerontol A Biol Sci Med Sci, 2023) [21]