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Endocrinology Targeting the central melanocortin system for the treatment of metabolic disorders 2023 DOI: 10.1038/s41574-023-00855-y PMID: 37365323 Sweeney P, Gimenez LE, Hernandez CC, et al

In humans, a randomized controlled clinical trial evaluated the effect of CoQ10 administration (300 mg/day, P.O for 12 weeks) on the antioxidant system in patients with coronary artery diseases

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Statements Author contributions AS: Conceptualization, Methodology, Resources, Writing original draft, Writing review & editing

Higher doses (2000 mg/day) likely saturate hepatic OCTN2 transporters and elevate intracellular carnitine sufficiently to activate CPT1-mediated fatty acid oxidation