PMID: 114 TabeY.HatanakaY.NakashiroM.SekiharaK.YamamotoS.MatsushitaH.et al
Magwenzi S, Woodward C, Wraith KS, Aburima A, Raslan Z, Jones H, McNeil C, Wheatcroft S, Yuldasheva N, Febbriao M, Kearney M, Naseem KM
The lessons from CVOTs Since 2016, five dedicated CVOTs have demonstrated a significant reduction in the three-point MACE (3P-MACE) composite outcome, encompassing non-fatal myocardial infarction, non-fatal stroke and cardiovascular death, in patients with type 2 diabetes receiving long-acting GLP-1RAs (Fig
3.6.3 Uncertainty management and the clinical pathway Beyond aggregate effects, the Bayesian framework offers a more intuitive representation of the potential range of individual response through posterior predictive distributions, effectively transforming heterogeneity from a statistical artifact into a tool for managing clinical uncertainty
Limit foods that worsen symptoms, such as high-fat fried foods, spicy foods, sugary beverages, processed foods, and alcohol, which can aggravate digestive discomfort
Myo-inositol effects in PCOS: meta-analysis of RCTs (Int J Endocrinol, 2016)Mixed randomized-trial support for oral myo-inositol on insulin-resistance markers in PCOS, at gram-level oral doses rather than injected MIC amounts