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consistent with the findings of a similar study, our results revealed that PFOS induced a concentration-dependent reduction in mitochondrial bioenergenesis, demonstrating that the administration of PFOA and PFOS (50200 M) induced the production of ROS, dissipation of mitochondria membrane potential, and apoptosis of HepG2 cells 31

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The growing interest in antioxidants has spurred the development of various methods to assess antioxidant activity in individual compounds and complex matrices such as foods, beverages, and body fluids

NQO1 metabolizing benzene, quinones, air pollution NAT1 and NAT2 N-acetyltransferases, cigarette smoke, hydrocarbons COMT adds methyl groups to modify endogenous substances, including estrogen, for elimination Elimination: Phase III Transporter Proteins Phase I and Phase II happen inside your cells, but once a metabolite has been made water-soluble, it still has to physically leave the cell and then the body