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Specifically, hazard ratios were 0.54 for insulin, 0.67 for metformin, 0.78 for SGLT2 inhibitors, 0.80 for older GLP-1RAs, 0.64 for sulfonylureas, 0.67 for thiazolidinediones, and 0.72 for DPP-4 inhibitors

The Lancet Gastroenterology & Hepatology

Step therapy (trying metformin or a sulfonylurea first) is the most common barrier

For international travel, carry a copy of your prescription and a letter from your prescriber

Key takeaways Semaglutide heartburn and acid reflux are possible, but not among the most common side effects of Ozempic and Wegovy

Hormonal modulators : buoyed by the success of therapeutically exploiting incretins, biotechs/pharma are exploring whether agonism of other GI hormones can similarly induce weight loss