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Studies have shown that supplementing with vitamin C can help maintain reduced glutathione (GSH) concentrations in the bloodstream and enhance the antioxidant protection capacity of the blood

The management of NCDs may be influenced by the interactions between antioxidants and metabolic enzymes (Table 1)

This increase in fat processing requires a steady supply of glutathione to prevent clogging the livers detoxification pathways

To answer it, they measured changes in key antioxidants both enzymes like superoxide dismutase (SOD) and glutathioneperoxidase (GPX), and molecules like glutathione (GSH) before and aftertraining

International Journal of Biochemistry and Cell Biology

However, as there are records of coffee enemas causing severe side effects and death, you should always speak with a doctor if youre considering an enema