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The most common side effect is a fishy body odor, caused by gut bacteria converting carnitine into trimethylamine

Martin SS, Aday AW, Allen NB, Almarzooq ZI, Anderson CAM, Arora P, et al

For pregnant and breastfeeding women, there is not enough research to confirm its safety, so experts recommend consulting a doctor before use (Saha et al., 2024)

its a systemic autoimmune disease

The progressive nature of comorbidity resolution, with continued improvements beyond the period of maximum WL, indicates that mechanisms beyond adiposity reduction contribute to these benefits

MC4R activity is also linked to sexual function, which explains why related peptides like PT-141 focus more on this pathway