Although there is consensus on a role for some mechanisms (regulation and signaling by the GRK-arrestin system), there are many examples of contradictory mechanisms
Translational Medicine of Aging, 2018
Regional specificity of aberrant thalamocortical connectivity in autism
As an illustration, it opposed hypertension and pro-thrombotic effects (L-NAME) [11,29,97,98,99], as well as hypotension and anti-thrombotic (L-arginine) effects [11,29,97,98,99]
Maintaining consistency in your treatment plan is key, but the choice remains flexible to suit your needs
While the use of methylene blue for these conditions sounds intriguing, it is important to remember that methylene blue is currently approved by the FDA only for the treatment of methemoglobinemia