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Elevated IL-6 and TNF- concentrations in CMS exposed mice demonstrate stress-induced inflammatory signaling contribution toward anxiety-like behaviors (Tyagi et al., 2025)

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55 This finding may be explained at least in part by reduced expression of the soluble guanylyl cyclase (sGC), as in different hypertensive animal models, the expression of one or both sGC subunits ( 1 and 1 ), as well as NO-dependent sGC activity were significantly decreased

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