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Our semaglutide storage guide covers this question in complete detail

Oral and injectable semaglutide both act on the same GLP-1 receptor pathway, but injectable versions are often associated with greater average weight loss due to more consistent dosing and higher bioavailability

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IV injections are typically done weekly in a 1ml to 4 ml volume and bring therapeutic levels within 24 hours

In some cases, if additional glycaemic control is needed, the dose may be increased to 2 mg weekly after at least four weeks on the 1 mg dose

In some individuals, the effects may resemble a condition called gastroparesis, where the stomach empties too slowly, leading to discomfort, poor appetite, or even vomiting