In some embodiments, the pharmaceutical formulations or compositions described herein are stable with respect to pH over a period of any of at least about 1 day, at least about 2 days, at least about 3 days, at least about 4 days, at least about 5 days, at least about 6 days, at least about 1 week, at least about 2 weeks, at least about 3 weeks, at least about 4 weeks, at least about 5 weeks, at least about 6 weeks, at least about 7 weeks, at least about 8 weeks, at least about 1 month, at least about 2 months, at least about 3 months, at least about 4 months, at least about 5 months, or at least about 6 months
The stakes are simply too high to accept theoretical risk
Kjell J, Olson L
Reciprocal interactions between endothelial cells and macrophages in angiogenic vascular niches
E., Abrams, J
Injection-site redness or irritation, transient lightheadedness or flushing, mild fatigue, and occasional nausea