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ATP evoked currents were also detected by sniffer patches placed in close proximity to primary L-cells following stimulation by various agonists of nutrient-sensing receptors expressed on L-cells including AMG-1638 (10 M), a selective free-fatty acid receptor 1 (FFA1) agonist, GPBAR-A (10 M), a selective agonist of the bile acid receptor GPBAR1, and peptones (3 mg ml 1

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The risk increases with both dose and duration

Potential Benefits of GLP-1s for Heart Health While the focus is often on potential risks, it is important to note that GLP-1 medications may offer significant secondary benefits for individuals already taking blood thinners for cardiovascular reasons