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Iodine deficiency disorders (IDD) are entirely preventable by ensuring an adequate daily intake of iodine [17, 18] (Fig

Lancet 391 , 319328 (2018)

The meta-analysis by Wang and colleagues 137 included an unpublished trial (NCT00845507 145 ) that was not part of the more recent meta-analysis by Khaity and colleagues 134

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Consequently, the commercial and regulatory strategy for MC4R-targeted therapies has logically shifted toward indications with more predictable and homogeneous patient populations

Food and Drug Administration (FDA) in 1990 and 1997, respectively, for the treatment of idiopathic growth hormone deficiency (GHD) in children with growth failure, or for evaluating the ability of the growth hormone producing cells, called somatotrophs, of the pituitary gland to secrete growth hormone