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Figure 5 Downstream cellular mediators of Dihexa protection Activation of the receptor tyrosine kinase c-Met leads to the recruitment of many signaling mediators and ultimately the activation of downstream signals, most notably Akt-TOR and Ras-ERK (Organ and Tsao, 6A)

This is understandable, as the field continues to prioritize data from double-blind, placebo-controlled, randomized, controlled trials (RCTs) as the benchmark for therapeutic adoption

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