4.4 Oxyntomodulin and natural dual agonism Oxyntomodulin, a peptide derived from the proglucagon gene alongside GLP-1 and glucagon, provides a compelling example of endogenous polypharmacology
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One study using a microphone-array-based system to help localize the source of USVs between paired interactions confirmed males and females both vocalize during courting [27]
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After 1 week of treatment, Fc-GLP1-injected mice showed an attenuated loss of body weight (11.0 0.46% versus 19.2 1.02) and adiposity compared to mice receiving G49 (Fig